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TFF Cassettes

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A wide variety of cassettes, of different sizes and membrane materials, are available (see specifications).


Characterization:

Minimate™ Tangential Flow Filtration Capsules
The easy-to-use Minimate TFF capsule is a valuable tool for any laboratory requiring tangential flow filtration of small process volumes. This versatile, ‘plug-and-play’, self-contained device (no holder required) is designed to operate with the Minimate™ TFF System or Minim™ II Tangential Flow Filtration System. It comes supplied with fittings and tubing to simplify installation into most small filtration setups. Sample batch sizes of up to one liter can be reduced to as low as 5 mL quickly and with little user intervention. Sample concentration and diafiltration (desalting) can take place sequentially using the same device and system, saving time and avoiding product loss associated with transfer steps. Minimate TFF capsules contain Pall’s proprietary Omega™ low non-specific adsorption UF membrane, available in a wide range of molecular weight cut-offs for improved  product recovery. Minimate TFF capsules can be used in a variety of TFF applications in biotechnology, molecular biology, protein chemistry, microbiology and immunology.

Omega™ T-Series Membrane Cassettes
T-Series membrane cassettes represent one of Pall’s latest advances in tangential flow filtration technology. These cassettes incorporate Pall’s proprietary Omega membrane with improvements in materials and design to optimize separation efficiency. Omega T-Series cassettes are available in our successful and long-established Centramate™ and Centrasette™ screen channel formats.

Omega™ C & F Series Cassettes
The long-established C & F Series TFF cassettes incorporate Omega UF membrane or Supor TFF MF membranes. These cassettes are available with Centramate, Centrasette, Maximate™ or Maxisette™ membranes, in both screen and suspended screen formats.

Centramate™ Tangential Flow Filtration Membrane Cassettes
Centramate™ TFF cassettes are perfect for laboratory-scale and development applications in TFF. Small area format (0.019 m2) can be used with Centramate™ LV Tangential Flow Filtration Membrane Cassette holders to process volumes of a few milliliters to several liters.

The larger, 0.1 m2 area cassettes fit in various Centramate holders where up to five cassettes can be stacked to process volumes from < 1 L to > 50 L. Applications developed on a Centramate cassette can be easily scaled up by stacking cassettes in a Centramate holder or by switching to the Centrasette cassette format with identical membrane, path length and channel format.

Centrasette™ Tangential Flow Filtration Membrane Cassettes
Centrasette TFF cassettes are available in the same range of membrane and screen formats as Centramate cassettes, but with a larger footprint and membrane area. These are ideal for pilot-scale or production-scale work in various tangential flow filtration applications, including concentration and diafiltration by the biopharmaceutical industry. These cassettes are available in several formats with membrane area of 0.5 mand 2.5 m2. Cassettes may be stacked in holders to build systems with membrane areas > 80 m2.

Maximate™ Tangential Flow Filtration Membrane Cassettes
Maximate TFF cassettes are available in the same membranes and screen and suspended screen formats as the Centramate/Centrasette cassettes. They offer the opportunity to simulate the performance of the larger Maxisette cassette on a smaller scale. Maximate cassettes have distinct benefits that make them advantageous as a development tool for larger-volume TFF processes.

Maxisette™ Tangential Flow Filtration Membrane Cassettes
Maxisette TFF cassettes offer the same benefits as the Maximate cassette for much larger volume processes.  The volumetric flow rate required is 40% lower compared to Centrasette cassettes.  The larger porting (almost 50% bigger) in the Maxisette provides lower resistance to high feed low rates which results in lower pressure drops and easier cleaning. The cassettes are offered in both screen and suspended screen formats with Omega UF or Supor TFF MF membranes.


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