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Microlab NIMBUS Select

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Hamilton Robotics and Coastal Genomics have partnered to combine the NIMBUS platform with RangerTechnology. The new NIMBUS Select workstation is the first option to fully automate size selection and analysis of nucleic acids using high throughput agarose gel electrophoresis. Scientists can now leverage high resolution fractionation for sample preparation and quality control in a fully automated, high throughput fashion.


Applications
  • Size selection for all types of NGS library preparation protocols
  • Analysis of PCR constructs, DNA smears and large fragments (>20kbp)
  • Isolation of genetic constructs to improve downstream processes (i.e. cloning)
  • High-yield recovery and effective rejection of off-target fragment lengths for cell-free circulating DNA

 

Benefits
  • High intrinsic recovery yields exceed 80%, ensuring even problematic samples can be salvaged
  • Unparalleled capacity for generation of electropherograms, with assay plate setup automated
  • Efficient rejection of off-target fragments (i.e. adaptermers, truncation products, chimeras) improves the value of downstream applications

 

Features
  • NIMBUS Select has the capacity to run 96 samples in a 2 hour Size Selection Mode run
  • High resolution analytics cassettes can accommodate 192 samples (384 capacity in development)
  • Modular Ranger Technology on-deck electrophoresis pedestals can be removed to conduct general liquid handling tasks with the 96 channel pipetting manifold
Technical Data:

Reagents:
Reagents Agarose Gel Cassettes*:
0.5%, 1.0%, 1.5%, 2.0%, 3.0%
Dual Dye Loading Mix*:
Customer selects a marker pair from over ten available Dual Dye markers.
*Contact Coastal Genomics for details on available Dual Dye markers and cassette resolution/accuracy
Workstation:
96 Channel Liquid
Handling Manifold
Range 1 μL – 1000 μL
Power Input: 100-250 VAC, 50-60 Hz, 5A
Physical Length: 41.0 in (104.1 cm)
Width: 28.0 in (71.1 cm)
Height: 34.5 in (87.6 cm)
Weight: 223 lbs (101.2 kg)
Ranger Control Computer:
Computer Input Input: 100-250 VAC, 50-60 Hz, 5A
Monitor Input 100-240 VAC, 50-60Hz, 1.6A
Ranger Imaging Hardware:
Camera Resolution 1280 x 960 pixels
Lighting Power Rating 8 Watts per color channel
System Includes:
NIMBUS 96 Workstation
Ranger Control
Computer
Coastal Genomics’
Ranger Software
Hamilton Robotics’ Microlab INSTINCT software
Hardware Package 1 Electrophoresis Pedestal
Ranger Tech Illumination and Imaging Assemblies


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