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Kleenpak™ Nova Prefilters

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The issues of effective cleaning and cleaning validation result in disposable equipment being the preferred option. For many processes, disposable filters can help eliminate cleaning problems, especially where biological products are to be filtered. Inbiopharmaceutical applicationswhere hazardous materials are being filtered, such as cytotoxic drugs, capsule filters can play an important role in helping protect operators.

Kleenpak Nova capsule filters are designed to provide choice, cost-effectiveness and flexibility, while ensuring ease of use for the operator.


Designed to Provide Choice and Flexibility

Kleenpak Nova capsule filters are available with either in-line or T-style configurations. The T-style configuration is ideal for manipulating multiple filters in series or parallel configuration.

Kleenpak Nova capsule filters incorporate either a 10 in. (254 mm), 20 in. (508 mm) or 30 in.
(762 mm) length standard Pall cartridge filters which have traditionally been installed in stainless steel housings. In applications where a particular filter is already specified, the user can switch from a stainless steel housing to a fully disposable assembly with minimal requalification. This means the extensive range of cartridges currently available from Pall for bioburden controlclarification and prefiltration can easily be provided as a capsule filter. These include:

  • PreFlow™ Filters
  • Ultipor® GF Plus Filters
  • Profile® Filters

Kleenpak Nova Filters Reduce Operating Costs

Kleenpak Nova filters have a typical installation cost that is 80% lower than a similar sized stainless steel housing system. Therefore, they offer an extremely cost-effective alternative to housing and cartridge systems. Kleenpak Nova filters can also provide further cost savings:

  • No housing maintenance — Lower maintenance costs
  • No housing cleaning or cleaning validation — Lower labor costs
  • Filter is pre-assembled — Lower labor costs
  • Filter can be provided pre-sterilized — Lower energy costs

Products in this datasheet may be covered by one or more patents including :
EP 0 667 800
EP 0 982 061
EP 1 380 331
US 5,543,047
US 5,690,765
US 5,725,784
US 6,113,784
US 7,083,564
US 7,318,800

Characterization:

Kleenpak Nova capsules are especially suited to pilot- and process-scale applications. They can be autoclaved or sterilized by gamma-irradiation and can be supplied as part of pre-sterilized processing systems such as a filter/tubing/bag set.

Kleenpak Nova capsules are used in a wide range of critical applications including the filtration ofbiopharmaceuticals, biologicals, diagnostic reagents, serum, tissue culture media, and culture media components.


Technical Data:

Operating Conditions

Maximum Operating Temperature 40 °C
Maximum Operating Pressure 3 barg (43.5 psig) at 40 °C in liquids1
0.5 barg for continuous gas service applications2

1 In compatible fluids which do not soften, swell or adversely affect the filter or its materials of construction
2 In case the pressure may exceed 0.5 barg (7 psig) during operation, a safety shield is required to protect operators and equipment in case of an accident. However, the maximum pressure of 3 barg (43.5 psig) must not be exceeded at any time

 

Capsule Materials of Construction

Housing Bowl  Polypropylene
Housing Head 2  Polypropylene
O-rings  Silicone elastomer

2 Formulated with TiO2 whitener which does not contribute to organic extractables.

 

Sterilization

 Autoclave (Maximum) ‘G’ Option Capsules: 3 x 1-hour cycles at 125 °C (257 °F)
 Gamma-irradiation Maximum Dosage  50 kGy

Consult Pall for procedures.

 

Nominal Dimensions

In Line NP6 NP7 NP8
Maximum Diameter including valves 154 mm (6.1 in.) 154 mm (6.1 in.) 154 mm (6.1 in.)
Length with hose barb inlet/outlet 397 mm (15.6 in.) 644 mm (25.4 in.) 895 mm (35.2 in.)
Length with sanitary inlet/outlet 335 mm (13.2 in.) 584 mm (23.0 in.) 834 mm (32.8 in.)
T Style NT6 NT7 NT8
Maximum Diameter including valves 240 mm (9.5 in.) 240 mm (9.5 in.) 240 mm (9.5 in.)
 Length 349 mm (13.7 in.) 598 mm (23.5 in.) 848 mm (33.4 in.)

Typical Flow Characteristics

Kleenpak Nova NP Capsule — Typical Water Flow Rates at 20 °C

Kleenpak Nova NT Capsule — Typical Water Flow Rates at 20 °C

Note: Empty Kleenpak Nova Capsule Housings for water at 20 °C, 1 cP. For other liquids, multiply pressure times the viscosity in centipoise. For complete assembly, including AB-Style filter cartridge, add housing, and cartridge media pressure-drop values, contact Pall for assistance.


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