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Core-shell technology for BIOSEPARATIONS.
Core-shell particle technology provides striking increases in peak capacity and resolution at lower backpressure, giving chromatographers the ability to achieve ultra-high performance on ANY system, HPLC or UHPLC.
A uniform porous silica layer is grown around a solid, spherical silica core, providing effective retention and selectivity with improved resolution, speed, and recovery. Next, optimizing the pore size and shell thickness for intact proteins or smaller peptide fragments provides well-defined depth penetration of biomolecules leading to maximum separation power.
TEM and SEM of Aeris™ PEPTIDE 3.6 µm Core-Shell Particles
The precise architecture of core-shell particles provides dramatic leaps in performance in two important ways:
The result is:
- 3.6 µm and 2.6 µm core-shell particles that can perform like sub-2 μm columns on both HPLC and UHPLC systems at a fraction of the pressure
- 2.6 µ and 1.7 µ core-shell particles that can provide higher peak capacities compared to fully porous sub-2 μm columns on UHPLC systems